Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.

By sequencing bacterial and archaeal genomes from single cells, scientists have filled in many uncharted branches of the tree of life.

Scientists transferred light-harvesting proteins into yeast for the first time, shining a light on the past lives of eukaryotic cells.

A study employing CRISPR/Cas9 to explore the evolutionary beginnings of some giant viruses finds evidence their large genomes arose from gene duplications.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

Advances in sequencing technologies have finally allowed researchers to zero in on the genetic diversity underlying the incredible mating system of shelf fungi.

Advances in the functional characterization of newly discovered microproteins hint at diverse roles in health and disease.

This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.