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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: CRISPR Proves Promising for Treating ALS in Mice

CRISPR Proves Promising for Treating ALS in Mice

By Katarina Zimmer | December 21, 2017

The gene-editing tool was effective in disabling a defective gene responsible for some forms of amyotrophic lateral sclerosis. 

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image: CRISPR Helps Mice Hear

CRISPR Helps Mice Hear

By Abby Olena | December 20, 2017

Researchers reduce the severity of hereditary deafness in mice with the delivery of CRISPR-Cas9 protein-RNA complexes that inactivate a mutant gene in their inner ears. 

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image: Hibernating Rodents Feel Less Cold

Hibernating Rodents Feel Less Cold

By Abby Olena | December 19, 2017

Syrian hamsters and thirteen-lined ground squirrels are tolerant of chilly temperatures, thanks to amino acid changes in a cold-responsive ion channel. 

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Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

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image: Image of the Day: Moth Resurrection

Image of the Day: Moth Resurrection

By The Scientist Staff | December 18, 2017

Entomologists have rediscovered a species of moth that was considered lost for 130 years. 

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image: Image of the Day: Actin Burst

Image of the Day: Actin Burst

By The Scientist Staff | December 6, 2017

Researchers are looking at actin polymerization and calcium uptake in human cells to study mitochondrial division.

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image: Image of the Day: Horseshoe Bat 

Image of the Day: Horseshoe Bat 

By The Scientist Staff | December 4, 2017

Factors such as humidity and temperature can affect how Rhinolophus clivosus use echolocation. 

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image: Captivated by Chromosomes

Captivated by Chromosomes

By Anna Azvolinsky | December 1, 2017

Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.

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image: In Situ Hybridization Explained

In Situ Hybridization Explained

By The Scientist Staff | December 1, 2017

Profilee Joseph Gall of the Carnegie Institute describes the process, which he developed in the 1960s.

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