Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.

George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.

By breaking down urea, the animals’ gut bacteria recycle nitrogen, which can be then used to build new molecules during prolonged fasting.

Life scientists are increasingly adopting the belief that microorganisms are virtually everywhere and are responsible for just about everything. This, plus the maturation of molecular- level methods of working with these tiny creatures, is a source of considerable optimism for microbiologists as the 93rd general meeting of the American Society for Microbiology (ASM) convenes in Atlanta this week. What they see, in career terms, is that progress in their field is bound to yield an ever-widening

Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.

Bacteria in the gut influence the production of antibodies and themselves secrete metabolites. In a pregnant woman, these compounds may influence immune development of her fetus.

Restoring natural capital As scientists and practitioners committed to ecological restoration, we found the analogy you made in your April issue1 between restoring natural capital (RNC)2 and new forms of cancer treatment3 to be an extremely powerful one. To a certain degree, RNC and ecological restoration in general, are indeed related to ecosystem degradation in the way that tumor ecology-based treatments are related to traditional cancer therapies, e.g., combined