Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.

Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.

From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.

Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.