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image: New Methods to Detect CRISPR Off-Target Mutations

New Methods to Detect CRISPR Off-Target Mutations

By Sandeep Ravindran | March 1, 2018

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

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Researchers identify antibodies for two commonly used Cas9 proteins in human blood. Investors take notice.

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image: Meet the Press, 1967

Meet the Press, 1967

By Kerry Grens | December 1, 2017

Fifty years ago, Arthur Kornberg announced to reporters that his team had synthesized functional DNA.

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image: 2017 Top 10 Innovations

2017 Top 10 Innovations

By The Scientist Staff | December 1, 2017

From single-cell analysis to whole-genome sequencing, this year’s best new products shine on many levels.

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By Kerry Grens | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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image: RNA Editing Possible with CRISPR-Cas13

RNA Editing Possible with CRISPR-Cas13

By Ruth Williams | October 25, 2017

Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells.

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Professionals in the genetics field generally support editing the genomes of somatic cells, mirroring public opinion, but diverge from nonexperts when it comes to germline editing.

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Scientists are using a powerful gene editing technique to understand how human embryos develop.

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image: Nonviral CRISPR Delivery a Success

Nonviral CRISPR Delivery a Success

By Abby Olena | October 2, 2017

Researchers use gold nanoparticles to deliver CRISPR-Cas9 and correct a point mutation in a mouse model of Duchenne muscular dystrophy. 

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