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tag virtual laboratory cell molecular biology immunology

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Virtual Laboratories for Remote Benchwork and Breakthroughs
The Scientist | Jan 26, 2024 | 2 min read
Scientists discuss the advent of robotically run research and the new era of academic cloud labs on the horizon.
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Image showing monoclonal antibody treatment
The Resilience of Monoclonal Antibodies and their Makers
Laura Tran, PhD | Mar 15, 2024 | 10+ min read
The road to developing monoclonal antibodies for effectively targeting cancer was paved with tenacity, passion, and strokes of luck.
A person moving the hands of a vintage clock backwards.
Synthetic Circuits Reveal the Key to Rewinding the Cellular Clock
Charlene Lancaster, PhD | Mar 12, 2024 | 4 min read
Using a circuit-based system, scientists determined the ideal transcription factor levels to promote the successful reprogramming of fibroblasts into induced pluripotent stem cells.
Biological Informatics: The Virtual Cell: Modeling Cellular Processes
Nadia Halim | May 9, 1999 | 4 min read
Biochemist John Carson uses The Virtual Cell to compare experimental and simulation results. Biologists are generating a vast amount of data on the molecular events that occur in the cell. Since a computer might the best tool for researchers to integrate all the information and sort out the complexities of a typical biological process, the next logical step would be to develop appropriate software for the job. A team at the University of Connecticut (UConn) Health Center in Farmington is attemp
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Immunology
The Scientist Staff | Feb 3, 1991 | 1 min read
J.J. Siekierka, S.H.Y. Hung, M. Poe, C.S. Lin, N.H. Sigal, "A cytosolic binding protein for the immunosuppressant FK-506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin," Nature, 341, 755-7, 26 October 1989. John J. Siekierka (Merck Sharp & Dohme Research Laboratories, Rahway, N.J.): "Two clinically important immunosuppressant drugs, cyclosporin A (CsA) and FK-506, are valuable probes for studying the molecular mechanisms of T cell activation. Although chemically uniqu
An Overview of High Throughput Screening
An Overview of High Throughput Screening
Tanvir Khan, PhD | Jan 2, 2024 | 5 min read
High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples. 
Immunology
The Scientist Staff | Apr 2, 1995 | 2 min read
Edited by: Neeraja D. Sankaran R.M. Chicz, R.G. Urban, J.C. Gorga, D.A.A. Vignali, W.S. Lane, J.L. Strominger, "Specificity and promiscuity among naturally processed peptides bound to HLA-Dr alleles," Journal of Experimental Medicine, 178:27-47, 1993. (Cited in 107 publications through January 1995) Comments by Roman M. Chicz,department of molecular and cellular biology, Harvard University One of the most important findings in this article, according to its authors, was the observation of pr

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