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image: Reprogrammed Cells Treat Diabetes in Mice

Reprogrammed Cells Treat Diabetes in Mice

By Abby Olena | May 2, 2018

Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By Kerry Grens | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Infographic: Macrophages Around the Body

Infographic: Macrophages Around the Body

By Claire Asher | October 1, 2017

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

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image: Macrophages Are the Ultimate Multitaskers

Macrophages Are the Ultimate Multitaskers

By Claire Asher | October 1, 2017

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

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image: Image of the Day: Mitochondria, Live and in Color

Image of the Day: Mitochondria, Live and in Color

By The Scientist Staff | September 27, 2017

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

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image: Engineered Human Liver Tissue Grows in Mice

Engineered Human Liver Tissue Grows in Mice

By Anna Azvolinsky | July 19, 2017

Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.

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image: Image of the Day: Liver Buds

Image of the Day: Liver Buds

By The Scientist Staff | June 16, 2017

Using human induced pluripotent stem cells, scientists grew liver organoids and studied gene expression patterns in individual cells to learn more about how these tissues develop. 

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image: Infographic: A Body Without Food

Infographic: A Body Without Food

By Bob Grant | June 1, 2017

Mounting evidence suggests that intermittent fasting causes significant changes to various organs and tissue types.

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Sangamo Therapeutics will use zinc finger nucleases to introduce the gene for a missing clotting factor into the livers of men with hemophilia B.

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image: Mouse Livers Grow and Shrink Daily

Mouse Livers Grow and Shrink Daily

By Abby Olena | May 4, 2017

Feeding-fasting rhythms and light-dark cycles direct regular changes in organ and cell size, as well as ribosome number and protein levels.

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