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tag sensory input genetics genomics immunology

Scientists Strike a Cord
Rabiya Tuma | Feb 9, 2003 | 6 min read
Courtesy of SR Eng  BABY STAINS: The head of a transgenic murine embryo in which a marker enzyme has been specifically expressed in the sensory neurons of the trigeminal and dorsal root ganglia. The marker allows staining of the projections of these neurons into, among other areas, the hindbrain and spinal cord. (S.R. Eng et al., "Defects in sensory axon growth precede neuronal death in Brn3a-deficient mice," J Neurosci, 21:541-9, 2001.) Somewhere in the 200 million bases of the human ge
The Infection Connection in Schizophrenia
Brendan Maher | Nov 2, 2003 | 7 min read
Adapted from image by I.I. Gottesman ©2001  GENES AND MORE: The risks of developing schizophrenia over a lifetime to the relatives of schizophrenia sufferers accord with a largely genetic explanation. Yet with 48% concordance for identical twins, environmental factors may play a role. It's a scary thought that one could develop a debilitating mental illness such as schizophrenia as easily as catching a cold. Well, it's more complicated than that, say advocates of the so-called infec
Assays Galore
Lanette Fee | Sep 21, 2003 | 9 min read
Courtesy of BD Biosciences Pharmingen  COLOR CODING: Multiplexed bead-based assays, like BD Biosciences' Cytometric Bead Array (shown), test for multiple analytes in a single vial. The key is in the colors: one hue indicates the bead ID, and the intensity of the second, how much protein has been captured. In today's fast-paced research environment, technologies for speedy, cost-efficient analyses reign supreme. As part of this general trend, techniques for multiplexing, that is, simultan

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