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tag hormones cell molecular biology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
Microscopic image of a live amoeba.
Illuminating Specimens Through Live Cell Imaging
Charlene Lancaster, PhD | Mar 14, 2024 | 8 min read
Live cell imaging is a powerful microscopy technique employed by scientists to monitor molecular processes and cellular behavior in real time.
Green and red fluorescent proteins in a zebrafish outline the animal’s vasculature in red and lymphatic system in green in a fluorescent image. Where the two overlap along the bottom of the animal is yellow.
Serendipity, Happenstance, and Luck: The Making of a Molecular Tool
Shelby Bradford, PhD | Dec 4, 2023 | 10+ min read
The common fluorescent marker GFP traveled a long road to take its popular place in molecular biology today.
Molecular Biology
The Scientist Staff | Aug 22, 1993 | 2 min read
M. Leid, P. Kastner, R. Lyons, et al., "Purification, cloning and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently," Cell, 68:377-95, 1992. Mark Leid (Oregon State University, Corvallis): "The diverse effects of retinoic acid (RA) on development, cellular growth and differentiation, and homeostasis are mediated by two families of RA receptors that arose independently during evolution and belong to the steroid/thyroid hormone super
MOLECULAR BIOLOGY
The Scientist Staff | Dec 8, 1991 | 2 min read
MOLECULAR BIOLOGY Date: December 9, 1991 D. Anderson, C.A. Koch, L. Grey, C. Ellis, et al., "Binding of SH2 domains of phospholipase Cg1, GAP, and Src to activated growth factor receptors," Science, 250:979-82, 1990. Tony Pawson (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto): "Many of the hormones that control cell growth, differentiation, and metabolism in the adult, and development in the embryo, bind to the extracellular region of receptors that span th
Molecular Biology
The Scientist Staff | Jan 20, 1991 | 3 min read
C.K. Glass, S.M. Lipkin, O.V. Devary, M.G. Rosenfeld, "Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer," Cell, 59, 697-708, 17 November 1989. Christopher K. Glass (School of Medicine, University of California, San Diego, La Jolla): "Retinoic acid receptors appear to exert profound effects on vertebrate development by binding to target genes and altering the rates at which they are transcribed in response to retinoic acid. Because t
Molecular Biology
The Scientist Staff | Mar 29, 1992 | 1 min read
C. Jonat, H.J. Rahmsdorf, K.-K. Park, A.C.B. Cato, S. Gebel, H. Ponta, P. Herrlich, "Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone," Cell, 62:1189-1204, 1990. Helmut Ponta (Kernforschungs-zentrum Karlsruhe, Germany): "Our paper was the first in a series that show that members of the steroid receptor family and the transcription factor AP-1 (Fos/Jun) mutually interfere with each other without change in DNA occupancy. Thus, bona fi
Collage of images including sperm, bacteria, coral, and an illustration of a researcher
Our Favorite Cell and Molecular Biology Stories of 2021
Jef Akst | Dec 2, 2021 | 3 min read
Beyond The Scientist’s coverage of COVID-19’s molecular underpinnings were many other stories highlighting the advances made in scientists’ understanding of the biology of cells.
A close up of several modular puzzle pieces.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD | Feb 13, 2024 | 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.

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