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tag estrogen developmental biology disease medicine

Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014 | 2 min read
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
A Ban on Estrogenics?
Jonathan Weitzman(jweitzman@the-scientist.com) | Aug 1, 2005 | 5 min read
California may soon become the first US state to adopt legislation banning the manufacture and sale of children's products containing certain chemicals designed to soften plastics.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Image of the tissue surrounding a pancreatic tumor thickening and scarring.
How Pancreas Injuries Can Cause Cancer in Mice
Dan Robitzski | Nov 9, 2021 | 4 min read
A key mutation turns healing cells into cancer promoters.
Woman smiling at the camera working out on a blue yoga mat.
Keeping Older Muscles Strong
Hannah Thomasy, PhD, Drug Discovery News | Sep 5, 2023 | 5 min read
From stem cell-recruiting gels to hormone cycle restoration, Tracy Criswell has big ideas about how to combat age-related decline in muscle regeneration.
Targeting Estrogen Receptor-B: A Case Study in Drug Discovery
Jennifer Fisher Wilson | May 18, 2003 | 10+ min read
 Models of estradiol (left) and genistein. For decades, researchers believed that a single estrogen receptor mediated the effects of estrogens in the body. So imagine their surprise when Jan-Åke Gustafsson of the Karolinska Institute in Stockholm announced at a 1996 Keystone symposium the discovery of a second estrogen receptor in the rat prostate. The revelation added unexpected complexity to scientists' understanding of estrogen's biological action. Many attendees scurried back to
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Monoclonal Antibodies Find Utility In Cell Biology
Ricki Lewis | Dec 11, 1994 | 10+ min read
But, just as antibodies are finding increasing utility in cell biology, a new Food and Drug Administration classification for those products with clinical utility may affect researchers' access to the important technology (see accompanying story). Monoclonal History MAbs were born in 1975, when Georges Kohler and Cesar Milstein at the Medical Research Council Laboratories in Cambridge, England, fused two types of cells to form a hy
Environmental Health Institute Blends Toxicology And Molecular Biology
Karen Young Kreeger | May 1, 1995 | 9 min read
Situated equidistant from Raleigh, Durham, and Chapel Hill, N.C.--smack in the middle of the Research Triangle--sits the only National Institutes of Health institutional campus outside of the Washington, D.C., Beltway. The National Institute of Environmental Health Sciences (NIEHS) is currently responsible for nearly 50 percent of all federally funded research on such subjects. It commands a diverse research agenda that covers populations and geographical boundaries far beyond the triangle or t
The AIDS Research Evaluators
Lynn Gambale | Jul 9, 1995 | 6 min read
Chairman: Arnold Levine, chairman, department of molecular biology, Princeton University Barry Bloom, Weinstock Professor and Howard Hughes Medical Institute (HHMI) investigator, department of microbiology and immunology, Albert Einstein College of Medicine, New York Rebecca Buckley, professor of pediatrics and immunology, Duke University Medical Center Charles Carpenter, chairman, Office of AIDS Research Advisory Committee; professor of medicine,Brown University School of Medicine Don

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