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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By Shawna Williams | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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Single-cell genome analyses reveal the amount of mutations a human brain cell will collect from its fetal beginnings until death.

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image: Captivated by Chromosomes

Captivated by Chromosomes

By Anna Azvolinsky | December 1, 2017

Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.

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image: Meet the Press, 1967

Meet the Press, 1967

By Kerry Grens | December 1, 2017

Fifty years ago, Arthur Kornberg announced to reporters that his team had synthesized functional DNA.

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image: Passing the Torch

Passing the Torch

By Mary Beth Aberlin | December 1, 2017

Looking back, looking forward

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: Six-Letter DNA Alphabet Produces Proteins in Cells

Six-Letter DNA Alphabet Produces Proteins in Cells

By Ruth Williams | November 29, 2017

Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.

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image: Image of the Day: Skate Youngsters 

Image of the Day: Skate Youngsters 

By The Scientist Staff | November 28, 2017

Scientists study the development of scales in skate embryos. 

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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