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image: Targeting the Noncoding Genome with CRISPR

Targeting the Noncoding Genome with CRISPR

By Anna Azvolinsky | September 29, 2016

Two independent groups demonstrate the utility of CRISPR-based techniques to identify regulatory elements that govern disease-linked genes. 

1 Comment

image: Geography of Genetic Diversity

Geography of Genetic Diversity

By Rina Shaikh-Lesko | September 29, 2016

Mammals and amphibians show greater intraspecific genetic diversity in the tropics compared with temperate regions.

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image: Does Productivity Diminish Research Quality?

Does Productivity Diminish Research Quality?

By Anna Azvolinsky | September 28, 2016

More papers correlate with top-cited research for more-established academics, but not newly minted professors, according to a study.  

3 Comments

image: “Out of Africa” Theory Gets the Genomic Treatment

“Out of Africa” Theory Gets the Genomic Treatment

By Bob Grant | September 26, 2016

A trio of genetic studies on seldom-studied indigenous populations points to a single wave of migration as humanity wandered from its evolutionary homeland into the rest of the world.

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image: Toggling CRISPR Activity with a Chemical Switch

Toggling CRISPR Activity with a Chemical Switch

By Kerry Grens | September 12, 2016

Researchers design a Cas9 enzyme that cuts DNA only in the presence of particular drug.

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image: Week in Review: September 5–9

Week in Review: September 5–9

By Jef Akst | September 9, 2016

Environmental magnetite in the human brain; prion structure takes shape; watching E. coli evolve in real time; learning from others’ behavior 

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Ancestries of nearly two dozen indigenous groups in the region reveal a close link between the genetic clustering of populations and the Kalahari Desert’s ecogeography.

3 Comments

image: Zika Update

Zika Update

By Bob Grant | September 7, 2016

Virus’s genome to aid in diagnoses; bees caught in crossfire of mosquito sprays; Zika spreads in Asia; US Congress revisits Zika funding

1 Comment

image: The History of Optogenetics Revised

The History of Optogenetics Revised

By Kerry Grens | September 1, 2016

Credit for the neuroscience technique has largely overlooked the researcher who first demonstrated the method.

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Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.

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