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tag protein engineering microbiology evolution

bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Different colored cartoon viruses entering holes in a cartoon of a human brain.
A Journey Into the Brain
Danielle Gerhard, PhD | Mar 22, 2024 | 10+ min read
With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.
Bugs as Drugs to Boost Cancer Therapy
Danielle Gerhard, PhD | Jan 18, 2024 | 7 min read
Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.
Promoting Protein Partnerships
Ruth Williams | Sep 1, 2016 | 3 min read
Scientists generate new protein-protein interactions at an impressive PACE.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
small striped mammal
Gut Microbes Help Ground Squirrels Endure Hibernation
Alejandra Manjarrez, PhD | Jan 27, 2022 | 4 min read
By breaking down urea, the animals’ gut bacteria recycle nitrogen, which can be then used to build new molecules during prolonged fasting.
Engineered Bacteria Build Carbon-Silicon Bonds
Joshua A. Krisch | Nov 28, 2016 | 1 min read
Researchers tweak bacterial proteins, turning them into powerful enzymes capable of producing silicon-carbon compounds naturally and more efficiently than manmade catalysts.
Julie Trolle and Jef Boeke
Self Sufficient Cells?
Katherine Irving | Jun 1, 2023 | 4 min read
Animal cells cannot produce 9 of the 20 amino acids they need to function. Some researchers are looking to change that.
Tree with many scattered branches.
Scientists Resurrect Ancient Rubiscos to Understand Their Evolution
Alejandra Manjarrez, PhD | Oct 14, 2022 | 5 min read
A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO2.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.

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