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tag protein engineering disease medicine immunology ecology

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
B cells secreting antibodies that target virus particles.
Stem Cell Editing Repairs Severe Immunodeficiency
Kamal Nahas, PhD | Mar 20, 2024 | 5 min read
Scientists hoping to treat immunodeficiencies using gene therapy have found a way to edit stem cells in mice without disrupting gene regulation.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
Carolyn Bertozzi working in the laboratory with postdoctoral scholar Ula Gerling-Driessen
Trimming Undruggable Cancer Targets
Deanna MacNeil, PhD | Sep 13, 2023 | 4 min read
Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.
Proteomics: Pushing Towards Single-Cell Resolution
Proteomics: Pushing Towards Single-Cell Resolution
The Scientist | Nov 3, 2022 | 1 min read
Learn how the latest single-cell proteomics technology is revolutionizing protein analysis and driving research progress.
Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.<br><br>
Immunotherapy Treats Fibrosis in Mice
Alejandra Manjarrez, PhD | Sep 15, 2022 | 4 min read
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

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