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tag pain neuroscience immunology

How Well Do Mice Model Humans?
Ricki Lewis | Oct 25, 1998 | 8 min read
STRIKING RESEMBLANCE: James Croom, who studies Down syndrome mice at North Carolina State University, says the animals are providing valuable information useful to humans. When a page-one article in the May 3, 1998, Sunday New York Times portrayed angiogenesis inhibitors that fight cancer in mice as being possible just around the corner for humans, criticism for raising false hopes erupted. Merely 10 weeks later, however, when researchers from the University of Hawaii reported cloning the fi
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l
Turmoil Besets Wistar In Wake Of Koprowski's Ouster
Jean Wallace | Mar 1, 1992 | 10+ min read
The Wistar Institute in Philadelphia marks its 100th anniversary this year, but the mood at the nation's oldest independent biomedical research facility is hardly jubilant. The institute has been in turmoil for the last year, after the abrupt ouster of longtime director Hilary Koprowski, the famed virologist and immunologist who transformed Wistar from a dilapidated museum into a world-renowned research center. The commotion recently was stirred up further, when the 75-year-old Koprowski file

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