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tag pain neuroscience

SYNGAP1 helps neurons eliminate old synapses and form new ones after a novel experience (left and center left)—a process weakened in mice missing a copy of the gene (center right and right).
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning
Angie Voyles Askham, Spectrum | Oct 26, 2021 | 4 min read
The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.
A series of brain scans on a black background
How Scientists Are Tackling Brain Imaging’s Replication Problem
Angie Voyles Askham, Spectrum | Jul 9, 2021 | 6 min read
Researchers who spoke with Spectrum say that while brain imaging tools have their limitations, they still hold promise in helping to unlock the brain’s secrets. 
How Manipulating Rodent Memories Can Elucidate Neurological Function
Amber Dance | May 1, 2020 | 10+ min read
Strategies to make lab animals forget, remember, or experience false recollections probe how memory works, and may inspire treatments for neurological diseases.
Book Excerpt from Behave
Robert Sapolsky | May 31, 2017 | 5 min read
In the book’s introduction, author and neuroendocrinologist Robert Sapolsky explains his fascination with the biology of violence and other dark parts of human behavior.
Capsule Reviews
Bob Grant | May 1, 2014 | 3 min read
Madness and Memory, Promoting the Planck Club, The Carnivore Way, and The Tale of the Dueling Neurosurgeons
Cloning the Capsaicin Receptor
Steve Bunk | Jan 23, 2000 | 3 min read
For this article, Steve Bunk interviewed David J. Julius, assistant professor of cellular and molecular pharmacology, University of California, San Francisco. Data from the Web of Science (ISI, Philadelphia) show that this paper has been cited significantly more often than the average paper of the same type and age. M.J. Caterina, M.A. Schumacher, M. Tominaga, T.A. Rosen, J.D. Levin, D. Julius, "The capsaicin receptor: a heat-activated ion channel in the pain pathway," Nature, 389:816-24, Oct. 2
Biophysics meeting roundup
Jef Akst | Mar 9, 2011 | 3 min read
Check out some highlights from this year's meeting of the Biophysical Society, held earlier this week
Notebook
Eugene Russo | Dec 5, 1999 | 7 min read
Contents Pivotal pump Leptin limbo Clue to obesity Biotech Web site Helping hand Mapping malaria Notebook Pictured above are pigmented bacterial colonies of Deinococcus radiodurans, the most radiation-resistant organism currently known. DEINO-MITE CLEANUP In 1956, investigators discovered a potentially invaluable cleanup tool in an unlikely place. A hardy bacterium called Deinococcus radiodurans unexpectedly thrived in samples of canned meat thought to be sterilized by gamma radiation. The b
Cannabinoid controversy
Tia Ghose | Sep 9, 2009 | 5 min read
Receptors that bind the active ingredient in marijuana may be novel therapeutic targets in autoimmune disease, but contested evidence for their presence on neurons could hamper drug development
Guiding light
Amber Dance | Dec 1, 2009 | 7 min read
ul li { font-family:"Trebuchet MS",arial,helvetica; font-size:10.5pt; line-height:14pt; } By Amber Dance Guiding light How to manipulate cellular events with the right light sensing molecule and a flash of light. Using light-producing molecules to observe cellular events is standard fare in many a lab, but it’s only recently that scientists have begun to harness the power of light to manipulate biological systems experimen

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