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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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Research in human patients and mice reveals the role of the circadian clock in the risk of heart damage at different times of day.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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image: Circadian Gene Linked to Severe Epilepsy in Children

Circadian Gene Linked to Severe Epilepsy in Children

By | October 11, 2017

Loss of the CLOCK protein, which researchers find is decreased in pediatric epilepsy patients, makes mice more prone to seizures during sleep.

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image: Q&A with Michael Young, Nobel Laureate

Q&A with Michael Young, Nobel Laureate

By | October 2, 2017

Young talks with The Scientist about studying circadian rhythms in fruit flies, the applications of his work beyond Drosophila, and winning the prize. 

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image: Q&A with Nobel Laureate Michael Rosbash

Q&A with Nobel Laureate Michael Rosbash

By | October 2, 2017

A basic curiosity about how life works led the Brandeis University molecular biologist to discover how our bodies keep time. 

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image: Giants of Circadian Biology Win Nobel Prize

Giants of Circadian Biology Win Nobel Prize

By | October 2, 2017

The award in Physiology or Medicine goes to chronobiologists Jeffrey Hall, Michael Rosbash, and Michael Young.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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