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hiv virus
HIV-1 Genome Extracted from 1966 Tissue Sample
Scientists spent five years reconstructing what is now the oldest HIV-1 genome yet recovered.
HIV-1 Genome Extracted from 1966 Tissue Sample
HIV-1 Genome Extracted from 1966 Tissue Sample

Scientists spent five years reconstructing what is now the oldest HIV-1 genome yet recovered.

Scientists spent five years reconstructing what is now the oldest HIV-1 genome yet recovered.

disease & medicine

human macrophage
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019 | 1 min read
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
cryopreservation facility
Immune Cell Bank Bets on Future CAR T Success
Nicoletta Lanese | Aug 16, 2019 | 6 min read
The company Cell Vault offers to hold consumers’ T cells for later use, but scientists suggest the service would benefit very few users.
schwann cells
Special Schwann Cells in Mice Play Unsung Role in Pain
Nicoletta Lanese | Aug 16, 2019 | 2 min read
The glia seem to make up part of a newly described sensory organ, the discoverers suggest.
Exercise Changes Our Gut Microbes, But How Isn’t Yet Clear
Ashley Yeager | Aug 15, 2019 | 5 min read
Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.
JHU Researchers Harmed Dogs, Animal Rights Group Argues
Ashley Yeager | Aug 15, 2019 | 2 min read
Stop Animal Exploitation Now issues a federal complaint against Johns Hopkins scientists, saying they messed up surgeries on nine animals.
First New Tuberculosis Drug Approved in 50 Years
Jef Akst | Aug 15, 2019 | 2 min read
The US Food and Drug Administration green lights a therapy for an extreme form of multidrug resistant TB.
novartis avexis zolgensma gene therapy fda manipulated data
Leaders of AveXis Out Over Doctored Gene Therapy Data
Kerry Grens | Aug 14, 2019 | 1 min read
Novartis, which bought the biotech firm in 2018, announced that the company’s top scientists have left, and news reports say it’s because they were involved in using manipulated data to get the gene therapy Zolgensma approved.
Trial in Africa Probes Antibiotic’s Effects on Child Mortality
Abby Olena, PhD | Aug 14, 2019 | 3 min read
In Niger, fewer kids die when health workers administer azithromycin routinely, perhaps because of a shift in the composition of gut microbes.
sei proteins help protect flies from heat-induced seizures
Image of the Day: Seizure Proteins
Nicoletta Lanese | Aug 14, 2019 | 1 min read
The sei ion channel in fruit flies keeps their neuronal excitability in check.
Two Experimental Drugs Effective at Treating Ebola
Catherine Offord | Aug 13, 2019 | 2 min read
REGN-EB3 and mAb114 reduced mortality in a clinical trial carried out during the ongoing outbreak in Democratic Republic of Congo.
Risk Factor 4 viruses shipped to China
Questions Surround Canadian Shipment of Deadly Viruses to China
Nicoletta Lanese | Aug 9, 2019 | 3 min read
The same Winnipeg lab that sent Ebola and Henipah viruses to Beijing recently removed a number of researchers for an “administrative issue.”
tweaking microbiome composition reduces colorectal tumor growth in mice
Image of the Day: Tamed Gut Bacteria
Nicoletta Lanese | Aug 8, 2019 | 2 min read
Curbing the growth of harmful bacteria in mouse microbiomes reduces the animals’ incidence of inflammation-related colorectal cancer.
gene therapy approval used manipulated data
Some Data Backing Novartis Gene-Therapy Approval Manipulated: FDA
Nicoletta Lanese | Aug 7, 2019 | 2 min read
The agency is now evaluating the implications of the corrupted data behind Zolgensma and whether to “take action” against the pharmaceutical company.
smartphone controlled device implanted in mouse brain
Image of the Day: Smartphone-Controlled Brains
Nicoletta Lanese | Aug 7, 2019 | 1 min read
A device implanted into mice can modulate brain circuit activity over long periods of time.
Microneedle patch delivers liquid medications
Image of the Day: Artificial Snake Bite
Nicoletta Lanese | Aug 6, 2019 | 1 min read
A microneedle delivers liquid medicines through tiny, fang-like points.
human embryo
First Human–Monkey Chimeras Developed in China
Nicoletta Lanese | Aug 5, 2019 | 3 min read
The researchers aim to grow transplantable human organs from primate embryos.
ebola vaccine uganda drc democratic republic of congo clinical trial
Uganda Launching New Experimental Ebola Vaccine Trial
Nicoletta Lanese | Aug 2, 2019 | 2 min read
Researchers aim to deploy the trial in neighboring Democratic Republic of Congo, which has been ravaged by Ebola for a year.
Virologist Keerti Shah Dies
Catherine Offord | Aug 2, 2019 | 3 min read
The Johns Hopkins University researcher’s work helped solidify the link between human papillomavirus and cervical cancer, leading to the approval of the HPV vaccine in 2006.
Survey of Stem Cell Clinics Reveals Cause for Concern
Jef Akst | Aug 1, 2019 | 4 min read
Two coauthors of a new study discuss their findings about nearly 170 facilities in the southwestern US selling unproven therapies—and what should be done about them.
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