disease & medicine

In a clinical trial, patients on the highest injected dose had 30 percent less cognitive decline over time than people on a placebo.

A Phase 1 clinical trial shows the noninvasive technique is safe and could aid in the delivery treatments to the brain.

Under one name the species is used in food fermentation, and under the other it is a drug-resistant cause of yeast infections.

Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.

Compared to other drugs, therapeutics given breakthrough status receive FDA approval on the basis of weaker trial evidence, a study finds.

The UK-based organization encourages public debate about the issue but does not recommend immediate policy change.

The adoption of machine-learning techniques to aid in diagnosis should be done with radiologists’ guidance.

The DNA-cutting enzyme used in the technique is not as precisely targeted as scientists had thought, and investors take notice.

In a longitudinal study, researchers find that elderly people with higher pressure were more likely to show signs of Alzheimer’s disease in brain tissue.

Levels of tau, amyloid-β 42, and IL-10 extracted from extracellular vesicles that started out in the brain were higher in military personal suffering head injuries compared with healthy soldiers.

Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies.

Despite the treatment being given for only six weeks, the positive effects lasted for a year.

Researchers discover cells in the early life stage of the Schistosoma mansoni parasite that contribute to adults’ reproductive systems.

Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.

Among 11 infants treated to date, most survived and their heart function improved.

An investigation by Politico finds the agency has been sitting on an assessment of formaldehyde’s cancer risks for a year and a half.

Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.

The coming legalization of recreational marijuana is already increasing funding for studies, but regulations on such research have been slow to change.

The Merck biochemist found the compound that led to a popular cholesterol-lowering drug.