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The Scientist

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Last year, researchers claimed the gene-editing method had accuracy issues, but a new whole-genome sequencing analysis by the same team finds otherwise.

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image: New Enzyme Makes CRISPR More Powerful

New Enzyme Makes CRISPR More Powerful

By Shawna Williams | March 2, 2018

xCas9 enables more precisely targeted gene editing.

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image: New Methods to Detect CRISPR Off-Target Mutations

New Methods to Detect CRISPR Off-Target Mutations

By Sandeep Ravindran | March 1, 2018

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

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image: CRISPR Trial for Cancer Patients Proposed

CRISPR Trial for Cancer Patients Proposed

By Katarina Zimmer | January 19, 2018

US researchers could become the first outside China to use the gene-editing technique in the clinic. 

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image: CRISPR Proves Promising for Treating ALS in Mice

CRISPR Proves Promising for Treating ALS in Mice

By Katarina Zimmer | December 21, 2017

The gene-editing tool was effective in disabling a defective gene responsible for some forms of amyotrophic lateral sclerosis. 

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image: CRISPR to Debut in Clinical Trials

CRISPR to Debut in Clinical Trials

By Diana Kwon | December 14, 2017

The first industry-sponsored CRISPR therapy is slated to be tested in humans in 2018.

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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By Ruth Williams | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By Ruth Williams | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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Professionals in the genetics field generally support editing the genomes of somatic cells, mirroring public opinion, but diverge from nonexperts when it comes to germline editing.

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image: Gene Drive Limitations

Gene Drive Limitations

By Jef Akst | October 9, 2017

In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.

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