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With CRISPR, Modeling Disease in Mini Organs
Tanya Lewis | May 6, 2016 | 3 min read
Organoids grown from genetically edited stem cells are giving scientists a new tool to screen drugs and test treatments.
Another Gene-Editing IPO
Bob Grant | Apr 12, 2016 | 2 min read
Intellia Therapeutics, which seeks to develop CRISPR-based technologies to target rare diseases, is hoping to raise $120 million in an initial public offering.
Human Embryos Genetically Edited Again
Kerry Grens | Apr 11, 2016 | 1 min read
For the second time, researchers use CRISPR to modify the genomes of nonviable embryos.
CRISPRi-Controlled Gene Expression
Jef Akst | Mar 10, 2016 | 2 min read
A variation of the gene-editing technique can more precisely and efficiently downregulate the expression of target genes than traditional CRISPR/Cas9.
Gene Editing Without Foreign DNA
Ruth Williams | Feb 1, 2016 | 2 min read
Scientists perform plant-genome modifications on crops without using plasmids.
More CRISPR Improvements
Jef Akst | Jan 25, 2016 | 1 min read
Researchers at the University of California, Berkeley, boost the CRISPR/Cas9 system’s gene-editing success rate in short pieces of DNA.
Who Owns CRISPR, Cont’d
Jef Akst | Jan 14, 2016 | 2 min read
The US Patent and Trademark Office declares a patent “interference” and will seek to determine who has rights to the gene-editing technology.
Cas9 Further Refined
Karen Zusi | Jan 7, 2016 | 2 min read
Researchers have engineered a Cas9 variant that produces almost no detectable gene-editing errors in the CRISPR/Cas9 system.
TS Picks: CRISPR Patent Edition
Kerry Grens | Jan 5, 2016 | 2 min read
A challenge to the first CRISPR patent just got teeth.
CRISPR Improves Disease in Adult Mice
Kerry Grens | Jan 4, 2016 | 2 min read
Three groups of researchers used the gene-editing method to restore a protein deficient in Duchenne muscular dystrophy.
Speaking of Science
The Scientist | Jan 1, 2016 | 2 min read
January 2016's selection of notable quotes
Top Technical Advances 2015
Kerry Grens | Dec 23, 2015 | 5 min read
The Scientist’s choice of major improvements in imaging, optogenetics, single-cell analyses, and CRISPR
Bayer Enters CRISPR Field
Karen Zusi | Dec 22, 2015 | 1 min read
The pharmaceutical company will spend $335 million on a new venture with biotech startup CRISPR Therapeutics.
GM Calves Move to University
Kerry Grens | Dec 21, 2015 | 1 min read
The first two bulls genetically engineered to lack horns arrived at the University of California, Davis, for breeding.
Year in Review: CRISPR Blossoms
Jef Akst | Dec 16, 2015 | 3 min read
As researchers work to improve the precision gene-editing technology, the community discusses the best way to use it.
CRISPR Therapy in a Dish
Kerry Grens | Dec 8, 2015 | 2 min read
Redirecting the gene-editing tool to modulate gene expression, researchers restore protein function in cells from a child with Duchenne muscular dystrophy.
The Scientist on The Pulse, December 4
Jef Akst | Dec 4, 2015 | 1 min read
Are precision gene editing technologies, such as CRISPR, ready for prime time?
Week in Review: November 30–December 4
Jef Akst | Dec 4, 2015 | 3 min read
Historic meeting on human gene editing; signs of obesity found in sperm epigenome; top 10 innovations of 2015; dealing with retractions
Let’s Talk Human Engineering
Jef Akst | Dec 3, 2015 | 4 min read
Experts continue to discuss the logistics and ethical considerations of editing human genomes at a historic meeting in Washington, DC.
Speaking of Science
The Scientist | Dec 1, 2015 | 2 min read
December 2015's selection of notable quotes