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image: Most Accurate CRISPR Gene Editing Yet

Most Accurate CRISPR Gene Editing Yet

By | September 22, 2017

A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.

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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: Details Published on CRISPR-treated Embryos

Details Published on CRISPR-treated Embryos

By | August 2, 2017

Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.

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image: Scientists Destroy Entire Chromosome with CRISPR

Scientists Destroy Entire Chromosome with CRISPR

By | August 1, 2017

Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.

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image: Human Genetic Variation May Complicate CRISPR

Human Genetic Variation May Complicate CRISPR

By | July 31, 2017

Slight sequence differences confound target sites in precision genome-editing, a study shows.

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image: Anti-CRISPR Protein Reduces Off-Target Effects

Anti-CRISPR Protein Reduces Off-Target Effects

By | July 12, 2017

AcrIIA4, an inhibitor protein from the Listeria bacteriophage, can block DNA from binding to Cas9 during genome editing.

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image: Was a Drop in CRISPR Firms’ Stock Warranted?

Was a Drop in CRISPR Firms’ Stock Warranted?

By | June 7, 2017

A study of off-target effects that sparked fear among investors of genome-editing companies receives methodological criticisms.

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image: Smallest Cas9 Ortholog Reported

Smallest Cas9 Ortholog Reported

By | February 23, 2017

Researchers demonstrate the delivery of AAV-packaged CRISPR-CjCas9 into the muscles and eyes of mice.

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image: Jeremy Day Probes Reward Signaling in the Brain

Jeremy Day Probes Reward Signaling in the Brain

By | January 1, 2017

The University of Alabama, Birmingham, researcher seeks the neural roots of animal behavior

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image: More Anti-CRISPR Proteins to Block Cas9

More Anti-CRISPR Proteins to Block Cas9

By | December 29, 2016

The latest CRISPR deactivators to be discovered turn off the Streptococcus pyogenes Cas9 widely used in genome editing.

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