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image: New Ovarian Cancer Vaccine Shows Promise

New Ovarian Cancer Vaccine Shows Promise

By Catherine Offord | April 12, 2018

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

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More than 200 people are on waiting lists for the $373,000 treatment as hospitals try to work around problems with insurers. 

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image: Gilead to Pay Nearly $12B for CAR T-Cell Company

Gilead to Pay Nearly $12B for CAR T-Cell Company

By Jef Akst | August 28, 2017

The massive sum will buy out Kite Pharma, whose cancer therapy is expected to be among the first of its type approved by the FDA.

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image: The Cancer Genes Needed for Immunotherapy Response

The Cancer Genes Needed for Immunotherapy Response

By Anna Azvolinsky | August 7, 2017

Using a large CRISPR-based screen, researchers find possible genetic culprits for patients not having success with immune checkpoint inhibitors.  

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In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 

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image: Gene Mutations Foretell Immunotherapy Response

Gene Mutations Foretell Immunotherapy Response

By Aggie Mika | June 12, 2017

A drug that blocks an immune checkpoint protein effectively treats tumors in patients with deficient DNA repair genes. 

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image: Hitting It Out of the Park

Hitting It Out of the Park

By Mary Beth Aberlin | April 1, 2017

Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.

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image: Making CAR T-Cell Therapy Safer

Making CAR T-Cell Therapy Safer

By Catherine Offord | April 1, 2017

Following a spate of patient deaths in clinical trials testing modified T cells for the treatment of cancer, researchers work to reduce the treatment’s toxicity without sacrificing efficacy.

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image: Tasmanian Devil Cancer Immunotherapy

Tasmanian Devil Cancer Immunotherapy

By Bob Grant | March 13, 2017

Researchers in Australia claim to have successfully used immunotherapy to treat devil facial tumor disease.

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image: Kite’s CAR T-Cell Therapy Success

Kite’s CAR T-Cell Therapy Success

By Jef Akst | March 1, 2017

More than one-third of lymphoma patients in a Phase 2 trial were clear of disease at six months, and no new safety concerns arose since the company’s three-month follow up.

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