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tag phosphorylation immunology

Keeping immunity in check
Megan Scudellari | Jun 16, 2011 | 2 min read
Two newly discovered proteins that act as brakes to slow a plant's immune response after infection may provide clues to autoimmune treatments.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018 | 10+ min read
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Escaping the Heat
Deborah Fitzgerald | Nov 12, 2000 | 10+ min read
Nonradioactive Kinase Assay Kits Safety concerns and economic considerations have fueled a growing trend in the biomedical sciences: to shun the use of radioactivity when practical. Nonradioactive options for numerous applications have become widely available, including a number of nonradioactive kinase assay kits. Assays from different manufacturers employ a wide range of strategies. Most of these kits utilize antibodies, but two nonimmunochemical approaches use fluorescently tagged substrates
Immunoassay Techniques Proven To Be Outstanding In Several Fields
Holly Ahern | Oct 1, 1995 | 10 min read
SIDEBAR: Selected Suppliers of Immunoassays and Assay Systems Immunoassays combine principles of immunology and chemistry into tests that are used by scientists in practically every discipline, including fields as diverse as molecular biology and environmental science. In research applications, immunoassays such as immunoblotting (detecting membrane-bound proteins), immunohistochemistry (cell or tissue staining), and enzyme immunoassays provide a sensitive and specific means of detecting targe
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Top 7 papers in cell biology
Jef Akst | Dec 5, 2010 | 3 min read
Just in time for ASCB -- see the cell biology articles most highly ranked by F1000
The Innate Immunity Adaptor List Grows
Aileen Constans(aconstans@the-scientist.com) | Jul 17, 2005 | 5 min read
Innate immunity, the first line of defense against infection, has revealed surprising complexity for what is considered a relatively primitive and conserved function.
Antibodies Making Their Way From The Clinic To The Research Lab
Holly Ahern | Sep 17, 1995 | 10 min read
if (n == null) The Scientist - The Immune Response The Scientist 9[18]:18, Sep. 18, 1995 Tools The Immune Response By Holly Ahern Imagine that you've just cloned a gene for a bacterial enzyme with unique structural properties and you want to find out more about it. What natural role does the enzyme play, you wonder, and do organisms other than bacteria produce it? To answer these questions, you could screen countless genomic libraries for clones bearing si
Mafia Wars
Jef Akst | May 31, 2010 | 10+ min read
An increasing amount of data is showing that the cellular battle between pathogens and hosts needs much more than a simple military metaphor to describe it—think undercover infiltration, front organizations, and forced suicide.
Cell-Signaling A Cascade of Kinases, Phosphatases, and Cytokines
Deborah Noble | Jul 4, 1999 | 8 min read
Date: July 5, 1999Table of Cell Signaling Tools At today's research pace, new signaling mechanisms within and between cells are emerging not one by one but in a chain reaction. Each new discovery has strong implications for previously established models, sometimes overturning several assumptions at once. With such a large number of interacting systems--from cell adhesion to differentiation and apoptosis--and receptor pathways, keeping up with the wealth of cell-signaling research tools can be l

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