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tag total internal reflection fluorescence tirf microscopy immunology

Upgrade Your Lab to TIRF
Jeffrey M. Perkel | Jun 1, 2006 | 4 min read
Why spend six figures on a new total internal reflection fluorescence system when you can upgrade your existing microscope for just $30,000?
TIRF Microscopy
Jeffrey M. Perkel | Jun 1, 2006 | 1 min read
/article/flash/23556/1/Click to view enlarged diagram Credit: ILLUSTRATION: ANDREW MEEHAN/ACKNOWLEDGEMENT: MICHAEL DAVIDSON" />/article/flash/23556/1/Click to view enlarged diagram Credit: ILLUSTRATION: ANDREW MEEHAN/ACKNOWLEDGEMENT: MICHAEL DAVIDSONStick a soda straw into a glass of water, and from the side, the straw will appear to bend at the interface between air and water. That effect is caused by the different refractive indexes of the air and water, which causes the li
Shedding Light on Cell Attachment
Shelby Bradford, PhD | Jan 8, 2024 | 3 min read
Cell adhesion may be initiated by small proteins previously viewed as helpers, not main players in attachment.
Sticking to the surface
Alla Katsnelson | Nov 1, 2007 | 2 min read
Related Articles Tips for choosing a microscope setup Going Live How it Works: Two-Photon Microscopy Pooling resources Prioritizing speed Mix and match Deep down view User: Warwick Nesbitt, a hematologist at Monash University in Melbourne, Australia. Project: Quantifying the adhesion footprint of platelets on proteins in the blood vessel cell wall. Problem: Achieving ultrahigh resolution. Solution: Nesbitt uses total internal reflection fluorescen
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
Next Generation: Super-Fast Tracking of Single Molecules
Ruth Williams | Nov 23, 2016 | 3 min read
A clever twist on a super-resolution microscopy technique improves the temporal resolution of single-molecule tracking. 
Exosomes Make Their Debut in Plant Research
Amanda Keener | Feb 1, 2019 | 10+ min read
A growing branch of research on how plants use exosomes to interact with their environment is opening up a new field of plant biology.
Top 10 Innovations 2013
The Scientist | Dec 1, 2013 | 10+ min read
The Scientist’s annual competition uncovered a bonanza of interesting technologies that made their way onto the market and into labs this year.
Squirmy Sperm
Kerry Grens | Nov 12, 2015 | 1 min read
Scientists observe another form of locomotion for male gametes, akin to a snake’s slither.
Scratching the Cell Surface
Aileen Constans | Nov 21, 2004 | 10 min read
Most biological microscopes delve deep into the cell, imaging optical slices that can be put together into a three-dimensional rendering of what lies beneath the cell membrane.

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