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Leonard Freedman, president of the Global Biological Standards Institute, discusses the causes of irreproducible science and his latest effort to spread best practices.

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image: Papers Based on Misidentified Cell Lines Top 32,000

Papers Based on Misidentified Cell Lines Top 32,000

By | October 16, 2017

An analysis of contaminated literature finds that tens of thousands of papers used cell lines of questionable origins—and these were in turn cited by hundreds of thousands of other papers.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: New Resource for Banked iPSCs

New Resource for Banked iPSCs

By | May 11, 2017

Researchers describe hundreds of induced pluripotent stem cell lines from healthy individuals. 

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: Henrietta Lacks’s Family Seeks Compensation

Henrietta Lacks’s Family Seeks Compensation

By | February 16, 2017

Family members of Lacks, the donor behind the widely used HeLa cell line, are planning to sue Johns Hopkins University.

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image: Popular Tumor Cell Line Contaminated

Popular Tumor Cell Line Contaminated

By | August 31, 2016

A commercially available glioblastoma cell line appears to be from a different source than its stated origins.

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image: Scientists Skip Cell Line Validation

Scientists Skip Cell Line Validation

By | October 12, 2015

Despite known problems with contamination and mislabeled cell lines, most researchers continue to operate without authenticating cells’ identity.

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image: The Great Big Clean-Up

The Great Big Clean-Up

By | September 1, 2015

From tossing out cross-contaminated cell lines to flagging genomic misnomers, a push is on to tidy up biomedical research.

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image: Seeded by Weeds

Seeded by Weeds

By | May 1, 2015

More than 50 years after cross-contamination of cultured cell lines was recognized, the problem continues to plague the scientific community.

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