epigenetics

The stressors a female rat experiences during pregnancy can have repercussions for her granddaughters, a study shows. 

Epigenetic and genetic changes in the SKA2 gene are correlated with suicidal behaviors, researchers show.

A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model. 

Assessing mtDNA mutations among healthy people; heritability of intelligence; epigenetic inheritance of maternal malnutrition markers; consumers buy into DNA ancestry

Mice undernourished during pregnancy can transmit the effects of such nutritional stress to their sons’ germ cells, epigenetically.  

Molecular markers of a mother’s nutrition around the time of conception can be found in her child’s DNA.

Genome-wide effects of trisomy 21; RNA-based signs of transgenerational stress; depression and resilience; a call to overhaul US biomedical research system

A mouse study shows that molecular remnants of early-life stress can be passed on to future generations.

Investigational drug that inhibits proteins involved with epigenetic regulation shows activity against certain blood cancers in an early-stage clinical trial.

A tour of techniques for measuring DNA hydroxymethylation

A mistimed sleep cycle drastically reduces the number of genes that are expressed in a 24-hour rhythm.

Mice appear to pass certain fears onto their offspring, according to a new study.

At the Society for Neuroscience conference, researchers present results linking the epigenome to heroin and cocaine addiction.

DNA methylation status can predict age in various human tissues, a study shows.

Visualizing specific epigenetic marks at single gene loci is now possible in individual cells.

The epigenetic modification of brain cells undergoes great shifts over the course of mouse and human development.

Females of the pair-bonded rodent species become attached to their lifelong mates following histone modifications near oxytocin and vasopressin receptor genes.

Highlights from a series of three webinars on the future of genome research, held by The Scientist to celebrate 60 years of the DNA double helix

A new technique could soon spur unprecedented insight into the role of bacterial epigenetics in the evolution of pathogen virulence.

Researchers track DNA modifications and gene expression in stem cells as they differentiate.