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image: Reprogrammed Cells Treat Diabetes in Mice

Reprogrammed Cells Treat Diabetes in Mice

By Abby Olena | May 2, 2018

Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

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image: Gene Therapy Temporarily Reverses Type 1 Diabetes in Mice

Gene Therapy Temporarily Reverses Type 1 Diabetes in Mice

By Shawna Williams | January 4, 2018

Pancreatic cells engineered to produce insulin did not immediately provoke an immune response.

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image: Immunotherapy Promising for Diabetes: Study

Immunotherapy Promising for Diabetes: Study

By Aggie Mika | August 9, 2017

A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.

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image: Image of the Day: Over the Islet Rainbow

Image of the Day: Over the Islet Rainbow

By The Scientist Staff | June 13, 2017

Scientists have constructed three-dimensional maps depicting the size and location of insulin-producing islet cells in the mouse pancreas.

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The diabetic volunteer continued to produce insulin one year after she received a transplant of abdominal islet cells.

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image: High-Profile Diabetes Study Retracted

High-Profile Diabetes Study Retracted

By Joshua A. Krisch | December 29, 2016

The results, which could not be replicated, suggested that a hormone increased pancreatic β cell proliferation, supplanting insulin as a front-line diabetes treatment in mice.

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image: How High Fat and Insulin Levels May Lead to Diabetes

How High Fat and Insulin Levels May Lead to Diabetes

By Barbara E. Corkey | July 1, 2016

Lipids and insulin play important roles in blood sugar regulation, and altered levels of either could kick start metabolic dysfunction.

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image: Insulin-Producing Mini Stomachs

Insulin-Producing Mini Stomachs

By Catherine Offord | February 22, 2016

Scientists grow gastric organs in vitro that can restore insulin production when transplanted into mice.

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image: Diabetes “Breakthrough” Breaks Up

Diabetes “Breakthrough” Breaks Up

By Kerry Grens | October 27, 2014

A hormone thought to make murine insulin-secreting cells proliferate in mice did not perform in replication studies.

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image: Lab-Made Insulin-Secreting Cells

Lab-Made Insulin-Secreting Cells

By Bob Grant | October 13, 2014

Researchers craft hormone-producing pancreas cells from human embryonic stem cells, paving the way for a cell therapy to treat diabetes.

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