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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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image: The Weird Growth Strategy of Earth’s First Trees

The Weird Growth Strategy of Earth’s First Trees

By Shawna Williams | October 24, 2017

Ancient fossils reveal how woodless trees got so big: by continuously ripping apart their xylem and knitting it back together.

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image: FDA Approves Second CAR T-Cell Therapy

FDA Approves Second CAR T-Cell Therapy

By Ashley P. Taylor | October 19, 2017

The therapy, produced by Kite Pharma and owned by Gilead Sciences, is approved for use against some types of large B-cell lymphomas. 

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image: Compound Found in Red Wine Boosts Immune Cell Function

Compound Found in Red Wine Boosts Immune Cell Function

By Catherine Offord | October 17, 2017

At low doses, resveratrol enhanced human T-cell activity in vitro, while at high doses it interfered with cell signaling. 

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image: Cancers Relapse by Feeding Off Immune Signals

Cancers Relapse by Feeding Off Immune Signals

By Shawna Williams | October 16, 2017

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

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image: Contributors

Contributors

By Aggie Mika | October 1, 2017

Meet some of the people featured in the October 2017 issue of The Scientist.

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image: Microglia Turnover in the Human Brain

Microglia Turnover in the Human Brain

By Shawna Williams | October 1, 2017

Researchers find that about a quarter of the immune cells are replaced every year.

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image: Do Pathogens Gain Virulence as Hosts Become More Resistant?

Do Pathogens Gain Virulence as Hosts Become More Resistant?

By Andrew F. Read and Peter J. Kerr | October 1, 2017

Emerging infections provide clues about how pathogens might evolve when farm animals are protected from infection.

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image: Infographic: Evolving Virulence

Infographic: Evolving Virulence

By Andrew F. Read and Peter J. Kerr | October 1, 2017

Tracking the myxoma virus in the wild rabbit populations of Australia has yielded insight into how pathogens and their hosts evolve.

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image: Infographic: Macrophages Around the Body

Infographic: Macrophages Around the Body

By Claire Asher | October 1, 2017

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

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