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Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.

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Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.

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image: Study: Eating Less Helps Worms Learn

Study: Eating Less Helps Worms Learn

By Aggie Mika | August 2, 2017

Food restriction decreases a metabolite that impedes associative learning in worms. 

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image: Running on Empty

Running on Empty

By Bob Grant | June 1, 2017

Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.

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image: Growth Hormone Guidance

Growth Hormone Guidance

By Jenny Rood | March 1, 2015

Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.

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