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image: 2017 Top 10 Innovations

2017 Top 10 Innovations

By | December 1, 2017

From single-cell analysis to whole-genome sequencing, this year’s best new products shine on many levels.

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More-sophisticated structures lend new insight into how Zika attacks the developing brain.

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image: Image of the Day: Goo for Growing Organoids

Image of the Day: Goo for Growing Organoids

By | October 24, 2017

Scientists engineered a synthetic, nutrient-rich gel that feeds growing organoids as they mature from human pluripotent stem cells into 3-D bowels.

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image: Image of the Day: Lab-Grown Brain

Image of the Day: Lab-Grown Brain

By | October 12, 2017

Scientists grew organoids that mimic human fetal brains and infected them with the Zika virus to model its neurological effects.

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image: Skin Graft-based Gene Therapy Treats Diabetes in Mice

Skin Graft-based Gene Therapy Treats Diabetes in Mice

By | August 4, 2017

A small patch of engineered cells makes an enzyme that stimulates insulin release.

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Mouse organoids reveal that a protein active during embryonic development joins forces with gene enhancers to revert cancer cells to an earlier developmental state.

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image: Engineered Human Liver Tissue Grows in Mice

Engineered Human Liver Tissue Grows in Mice

By | July 19, 2017

Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.

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image: Image of the Day: Liver Buds

Image of the Day: Liver Buds

By | June 16, 2017

Using human induced pluripotent stem cells, scientists grew liver organoids and studied gene expression patterns in individual cells to learn more about how these tissues develop. 

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image: Image of the Day: Ears-in-a-Dish

Image of the Day: Ears-in-a-Dish

By | May 2, 2017

Using three-dimensional culture, which allows cells to grow in a ball-shape aggregate, scientists created inner ear organoids containing sensory neurons and hair cells.

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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