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Increased Neuronal Activity Shortens Lifespan in Animals
Increased Neuronal Activity Shortens Lifespan in Animals
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
longevity, genetics & genomics
C. elegans Healthier Without Longevity Gene
Chia-Yi Hou | Jul 17, 2019 | 2 min read
Worms with the reproduction-related TCER-1 gene deleted could fight off infection for longer and survived better when exposed to heat and radiation.
Genetic Mutation that Prevents HIV Infection Tied to Earlier Death
Emma Yasinski | Jun 3, 2019 | 3 min read
Those with two copies of the Δ32 allele in the CCR5 gene are 21 percent more likely to die by age 76, although it’s not clear why.
Master Decoder: A Profile of Kári Stefánsson
Anna Azvolinsky | Mar 1, 2019 | 9 min read
A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.
Another Bird Telomere Study, Different Results
Anna Azvolinsky | Mar 21, 2018 | 2 min read
Two studies examining the effects of parents’ ages on their offsprings’ telomere lengths come to opposite conclusions.
Study: Telomeres Don’t Shorten with Age in Longest-Lived Bats
Diana Kwon | Feb 7, 2018 | 1 min read
Researchers find that while bats in the Myotis genus don’t produce telomerase, the enzyme that lengthens telomeres, they possess 21 telomere maintenance–related genes.
Fingerprints of Ongoing Human Evolution Found
Shawna Williams | Sep 5, 2017 | 4 min read
Genetic variants in Alzheimer’s- and smoking-related genes appear to be under selection pressure, according to a study comparing the genomes of old and young participants.
Mutation Linked to Longer Life Span in Men
Jef Akst | Jun 18, 2017 | 2 min read
A deletion in a growth hormone receptor gene is tied to an average of 10 extra years of life among men, but not women, according to a study.
First Data from Anti-Aging Gene Therapy
Kerry Grens | Apr 25, 2016 | 4 min read
A biotech company reports that an experimental treatment elongated its CEO’s telomeres.
Methylation Predicts Mortality
Kerry Grens | Feb 3, 2015 | 1 min read
A study finds a link between patterns of methylation in the human genome and people’s life span.
Longevity Study Lives On
Cristina Luiggi | Jan 24, 2012 | 1 min read
A reanalysis of the study reporting genes linked to extremely long life, which was retracted from Science last summer, is published in PLoS ONE.
Longevity Paper Retracted
Tia Ghose | Jul 21, 2011 | 2 min read
A study that identified several genes linked to extremely long life has been retracted due to technical errors in the sequencing chips used.