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tag genome wide association study microbiology genetics genomics

DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 
Colored Genetic Code DNA Molecule Structure stock photo
Genetic Risks for Depression Differ Between Ancestral Groups
Chloe Tenn | Oct 19, 2021 | 4 min read
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
Twisted DNA Increases CRISPR Off-target Effects
Shelby Bradford, PhD | Feb 8, 2024 | 4 min read
Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Cartoon of the gut with different colored bacteria and a magnifying glass hovering over part of the gut.
Humans Rely on Gut Bacteria for an Enzyme that Prevents Jaundice
Kamal Nahas, PhD | Feb 16, 2024 | 5 min read
An absence of bilirubin-producing gut microbes may predispose individuals to some diseases, including inflammatory bowel disease.
Trisomy 21 Effects Seen Genome-wide
Rina Shaikh-Lesko | Apr 16, 2014 | 3 min read
The extra chromosome behind Down’s syndrome can impact transcriptional regulation beyond chromosome 21, a study finds.
Genetic Spectra of Schizophrenia
Tracy Vence | Sep 16, 2014 | 2 min read
An analysis of three independent genome-wide association studies suggests schizophrenia is a group of heritable disorders associated with distinct clinical syndromes.
a Hawaiian bobtail squid (Euprymna scolopes) resting on a reflective surface
Reshuffled Genomes May Explain Cephalopods’ Smarts
Sophie Fessl, PhD | May 13, 2022 | 4 min read
In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.
A green and white fish swimming underwater
Rockfish Genes Hold Clues to Human Longevity
Natalia Mesa, PhD | Jan 12, 2023 | 3 min read
By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.
A fishing cat with a fish in its mouth
Genome Spotlight: Fishing cat (Prionailurus viverrinus)
Christie Wilcox, PhD | Dec 22, 2022 | 5 min read
A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.

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