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With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

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Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.

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image: CRISPR: No Cutting Required

CRISPR: No Cutting Required

By | August 4, 2016

Combining a modified Cas9 enzyme with an unrelated one derived from the immune system of the sea lamprey, researchers demonstrate yet another way to edit a single DNA nucleotide. 

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image: Advances in Genome Editing

Advances in Genome Editing

By | April 20, 2016

Researchers develop a CRISPR-based technique that efficiently corrects point mutations without cleaving DNA.

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