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Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

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image: Cancer Evolutionist: A Profile of Charles Swanton

Cancer Evolutionist: A Profile of Charles Swanton

By Anna Azvolinsky | April 1, 2018

Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.

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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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Errors in segregation during cell division can lead to inflammation in daughter cells.

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image: Genetic Mutation Linked to Cot Death

Genetic Mutation Linked to Cot Death

By Catherine Offord | March 29, 2018

Alterations to a protein involved in breathing may help explain some cases of sudden infant death syndrome, a study finds.

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Last year, researchers claimed the gene-editing method had accuracy issues, but a new whole-genome sequencing analysis by the same team finds otherwise.

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The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.

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A study finds that the vaccine’s effects wear off as a person ages, suggesting a need for booster shots.

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DNA analysis gives clues to how the ancient hominin’s population split and how they interacted with modern humans.

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image: Kathy Matthews, <em>Drosophila</em> Geneticist, Dies

Kathy Matthews, Drosophila Geneticist, Dies

By Kerry Grens | March 20, 2018

For decades, Matthews led two important repositories for fruit fly research: the Bloomington Drosophila Stock Center and FlyBase.  

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