Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

A new platform for screening astrocyte reactivity helps researchers uncover potential therapeutic interventions to treat neurodegenerative conditions.

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

With the help of directed evolution, scientists inch closer to developing viral vectors that can cross the human blood-brain barrier to deliver gene therapy.

Paola Arlotta seeks to understand the complex symphony of brain development in vitro by using organoid models.

A new study confirms reports of membrane-bound RNA molecules and points to their role in neutrophil migration.

Drawing inspiration from nature, synthetic biology offers exciting opportunities to transform the future of medicine.

This year’s Breakthrough Prizes honor advances in CAR T cancer therapies, cystic fibrosis, and Parkinson’s disease.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.