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image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By Jef Akst | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

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image: Top Technical Advances in 2017

Top Technical Advances in 2017

By Shawna Williams | December 25, 2017

The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.

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image: Vitamin C Depletion Accelerates Leukemia in Mice

Vitamin C Depletion Accelerates Leukemia in Mice

By Aggie Mika | August 21, 2017

High levels of vitamin C absorbed by blood-forming stem cells are important for their normal development. 

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image: Vitamin C Blocks Leukemia Progression in Mice

Vitamin C Blocks Leukemia Progression in Mice

By Aggie Mika | August 17, 2017

High-dose vitamin C injections reverse the effects of a leukemia-promoting genetic deficiency.

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image: Blood Stem Cells Grown in the Lab

Blood Stem Cells Grown in the Lab

By Ashley Yeager | May 17, 2017

Researchers identify transcription factors and environmental conditions necessary to reprogram human and mouse cells into cells that function like hematopoietic stem cells.

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image: Synthetic Bones: A Better Bone-Marrow Transplant?

Synthetic Bones: A Better Bone-Marrow Transplant?

By Ashley P. Taylor | May 9, 2017

Artificial bones produce new blood cells in mice, obviating the need for irradiation to kill off resident hematopoietic stem cells in recipients.

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image: How to Track Cell Lineages As They Develop

How to Track Cell Lineages As They Develop

By Kelly Rae Chi | December 1, 2016

Sequencing and gene-editing advances make tracing a cells journey throughout development easier than ever.

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image: More Success Fixing Sickle Cell Gene with CRISPR

More Success Fixing Sickle Cell Gene with CRISPR

By Kerry Grens | November 9, 2016

Researchers say they have sufficient in vitro and animal data to apply for human testing.

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image: TS Picks: August 9, 2016

TS Picks: August 9, 2016

By Bob Grant | August 9, 2016

Gene therapy money-back guarantee; the brain benefits from bilingualism; Q&A with a science watchdog

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