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image: CT Scans Increase Risk of Cancer

CT Scans Increase Risk of Cancer

By Edyta Zielinska | June 7, 2012

Exposure to doses of radiation used in some diagnostics in childhood can triple the risk of brain cancer and leukemia as an adult.

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image: Designing Transition-State Inhibitors

Designing Transition-State Inhibitors

By Vern L. Schramm | May 1, 2012

A transition-state mimic has the power to bind an enzyme at its tipping point as strongly as any available inhibitor and more strongly than most, preventing enzymatic activity. 


image: Freezing Time

Freezing Time

By Vern L. Schramm | May 1, 2012

Targeting the briefest moment in chemistry may lead to an exceptionally strong new class of drugs.


image: Telomeres in Disease

Telomeres in Disease

By Rodrigo Calado and Neal Young | May 1, 2012

Telomeres have been linked to numerous diseases over the years, but how exactly short telomeres cause diseases and how medicine can prevent telomere erosion are still up for debate.


image: Are Cancer Stem Cells Ready for Prime Time?

Are Cancer Stem Cells Ready for Prime Time?

By Suling Liu, Hasan Korkaya, and Max S. Wicha | April 1, 2012

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.


image: Turning T-cells into Cancer Killers

Turning T-cells into Cancer Killers

By Tia Ghose | August 10, 2011

Repurposing patient’s own T-cells to recognize antigens on cancer cells caused dramatic improvement in three patients with chronic lymphocytic leukemia.


image: Stem Cells Hit Reverse

Stem Cells Hit Reverse

By Tia Ghose | July 31, 2011

A transcription factor can make adult stem cells behave like fetal stem cells.


image: Interfering with Cancer

Interfering with Cancer

By Katherine Hyde and Paul Liu | January 1, 2011

MicroRNAs may drive the development of leukemia.


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