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image: Anti-CRISPR Protein Reduces Off-Target Effects

Anti-CRISPR Protein Reduces Off-Target Effects

By | July 12, 2017

AcrIIA4, an inhibitor protein from the Listeria bacteriophage, can block DNA from binding to Cas9 during genome editing.

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In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 

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image: RNA Protects “Naked” Genomes from Retrotransposons

RNA Protects “Naked” Genomes from Retrotransposons

By | June 30, 2017

Transfer RNA fragments prevent jumping genes from hopping around in the mouse embryo, when histone methylation can’t do the job.

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The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

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The International Mouse Phenotyping Consortium aims to characterize the entire mouse genome, starting first with more than 3,300 genes. 

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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By spreading a poison and hoarding the remedy, wtf4 improves its chances of being inherited. 

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Genomic analysis of an oak tree that lived during Napoleon’s time supports the idea that plants somehow avoid the accumulation of mutations in their stem cells.

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The discovery of peptides, enzymes, and other gene products that confer antibiotic resistance could give clues to how it develops.

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image: Mutation Linked to Longer Life Span in Men

Mutation Linked to Longer Life Span in Men

By | June 19, 2017

A deletion in a growth hormone receptor gene is tied to an average of 10 extra years of life among men, but not women, according to a study.

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