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image: Fanning the Flames

Fanning the Flames

By Kate Yandell | November 1, 2015

Obesity triggers a fatty acid synthesis pathway, which in turn helps drive T cell differentiation and inflammation.

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image: Breaking the Cancer-Obesity Link

Breaking the Cancer-Obesity Link

By Stephen D. Hursting, Ciara H. O’Flanagan, and Laura W. Bowers | November 1, 2015

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

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image: Obesogens

Obesogens

By Kerry Grens | November 1, 2015

Low doses of environmental chemicals can make animals gain weight. Whether they do the same to humans is a thorny issue.

3 Comments

image: A Complex Disorder

A Complex Disorder

By Stephen D. Hursting, Ciara H. O’Flanagan, and Laura W. Bowers | November 1, 2015

Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.  

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image: Fat Factors

Fat Factors

By Kerry Grens | November 1, 2015

A mouse's exposure to certain environmental chemicals can lead the animal—and its offspring and grandoffspring—to be overweight.

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image: Not Immune to Fat

Not Immune to Fat

By Kate Yandell | November 1, 2015

The effect of a high-fat diet on murine T cells

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image: Latest in Heart Stem Cell Debate

Latest in Heart Stem Cell Debate

By Kerry Grens | October 26, 2015

Given the right environment, cKit+ cells from the mouse heart can develop into new cardiac muscle, according to a study.

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image: Antioxidants May Aid Cancer

Antioxidants May Aid Cancer

By Kerry Grens | October 16, 2015

Mice given a dietary supplement had faster-progressing melanoma, a study shows.

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image: Growing Placenta-Generating Cells

Growing Placenta-Generating Cells

By Jef Akst | October 14, 2015

Researchers derive trophoblast stem cells from mouse fibroblasts, paving the way for cell therapy for placental dysfunction diseases.

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image: Explaining Elephants’ Cancer Resistance

Explaining Elephants’ Cancer Resistance

By Jef Akst | October 13, 2015

Two studies reveal that the giant mammals have dozens of extra copies of a cancer-preventing gene.

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