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image: The Role of DNA Base Modifications

The Role of DNA Base Modifications

By | September 1, 2017

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

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image: Dengue Infection Impairs Immune Defense Against Zika

Dengue Infection Impairs Immune Defense Against Zika

By | August 18, 2017

A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.

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image: Tiny Motors Deliver Ulcer Medication in Mouse Stomachs

Tiny Motors Deliver Ulcer Medication in Mouse Stomachs

By | August 17, 2017

The mini machines treated infection somewhat better than antibiotics plus the typical proton pump inhibitor medication. 

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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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image: Right-to-Try Bill Passes the Senate

Right-to-Try Bill Passes the Senate

By | August 4, 2017

The legislation removes restrictions for seriously ill patients to access experimental treatments that have not received FDA approval.

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image: Fascinated by Folding

Fascinated by Folding

By | August 4, 2017

Lila Gierasch uses biochemical tools to understand how linear chains of amino acids turn into complex three-dimensional structures.

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image: Dogs with Duchenne Treated with Gene Therapy

Dogs with Duchenne Treated with Gene Therapy

By | July 25, 2017

Researchers restored muscle function in animals with muscular dystrophy.

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A new method stimulates B cells to make human antigen-specific antibodies, obviating the need for vaccinating blood donors or hunting for rare B cells.

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  4. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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