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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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If approved, patisiran will be the first RNAi therapeutic on the market. 

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image: Image of the Day: Tadpole Prism

Image of the Day: Tadpole Prism

By | November 3, 2017

Scientists are making use of Xenopus tadpoles to study autism risk genes. 

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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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image: Image of the Day: Fragile Brain

Image of the Day: Fragile Brain

By | October 3, 2017

In Fragile X syndrome—a genetic mishap that results in cognitive delays—the lack of a translation-repressing protein leads to the rampant accumulation of other proteins in the mouse brain.

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image: Infographic: Macrophages Around the Body

Infographic: Macrophages Around the Body

By | October 1, 2017

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

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image: Macrophages Are the Ultimate Multitaskers

Macrophages Are the Ultimate Multitaskers

By | October 1, 2017

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

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image: Water Level in a Cell Can Determine Its Fate

Water Level in a Cell Can Determine Its Fate

By | September 27, 2017

Adding or removing water changes how stem cells differentiate.

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image: CRISPR Used in Human Embryos to Probe Gene Function

CRISPR Used in Human Embryos to Probe Gene Function

By | September 20, 2017

OCT4 is necessary for blastocyst formation in the human embryo, researchers report.

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    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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