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image: Opinion: Label Drugs That Are Tested on Animals

Opinion: Label Drugs That Are Tested on Animals

By | January 16, 2018

Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.

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The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

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image: Maternal Response to Zika Damages Mouse Fetuses

Maternal Response to Zika Damages Mouse Fetuses

By | January 5, 2018

Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.

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image: Alcohol Damages Mouse DNA

Alcohol Damages Mouse DNA

By | January 3, 2018

A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.

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image: Child Receives Transgenic Skin

Child Receives Transgenic Skin

By | January 1, 2018

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.

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image: Contributors

Contributors

By | January 1, 2018

Meet some of the people featured in the January 2018 issue of The Scientist.

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image: David Julius Probes the Molecular Mechanics of Pain

David Julius Probes the Molecular Mechanics of Pain

By | January 1, 2018

For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Painful Realities

Painful Realities

By | January 1, 2018

Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.

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image: Sex Differences in Opioid Analgesia: A Complicated Picture

Sex Differences in Opioid Analgesia: A Complicated Picture

By | January 1, 2018

Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.

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