A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.
For nearly 30 years, the UC San Francisco researcher has delved into unexplored corners of the nervous system.
Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.
Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.
Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
A cornucopia of toxins in the animal kingdom could provide inspiration for novel painkillers, but so far, effective drugs have proven elusive.
Decades after their discovery by bioprospectors, amphibian-derived analgesics continue to attract scientific attention.
Arachnids harbor a plentiful array of molecules that target mammalian pain receptors.
Studying cone snail venom has yielded novel pain pathways, but the peptides that function as toxins are difficult to translate into drugs.
After implantation, the tissue developed blood vessels and became integrated into neuronal networks in the animals’ brains.
The nationwide experiment will initially include around 100,000 volunteers.
The 20-year project calls into question the conventional wisdom about the role plants will play in mitigating future climate change.
The US Senate narrowly approved the politician, who does not have a science background.
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