The Scientist

» drug development and genetics & genomics

Most Recent

image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

0 Comments

image: Painful Realities

Painful Realities

By | January 1, 2018

Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.

0 Comments

image: Sex Differences in Opioid Analgesia: A Complicated Picture

Sex Differences in Opioid Analgesia: A Complicated Picture

By | January 1, 2018

Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.

0 Comments

image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

0 Comments

image: Animal Analgesics

Animal Analgesics

By | January 1, 2018

A cornucopia of toxins in the animal kingdom could provide inspiration for novel painkillers, but so far, effective drugs have proven elusive.  

0 Comments

image: Frog Skin Yields Potent Painkillers, but None Clinic Ready

Frog Skin Yields Potent Painkillers, but None Clinic Ready

By | January 1, 2018

Decades after their discovery by bioprospectors, amphibian-derived analgesics continue to attract scientific attention.

0 Comments

image: Mining Spider Toxins for Analgesic Clues

Mining Spider Toxins for Analgesic Clues

By | January 1, 2018

Arachnids harbor a plentiful array of molecules that target mammalian pain receptors.

0 Comments

image: Novel Analgesics at a Snail’s Pace

Novel Analgesics at a Snail’s Pace

By | January 1, 2018

Studying cone snail venom has yielded novel pain pathways, but the peptides that function as toxins are difficult to translate into drugs.

0 Comments

image: Researchers Mine Centipede Toxins for Analgesics

Researchers Mine Centipede Toxins for Analgesics

By | January 1, 2018

Venomous centipedes may harbor a clue to the creation of a successful pain-killing compound for humans.

0 Comments

image: Sea Anemone Toxin Could Treat Autoimmunity

Sea Anemone Toxin Could Treat Autoimmunity

By | January 1, 2018

If successful, the treatments could alleviate patients’ pain by reducing inflammation.

0 Comments

Popular Now

  1. Secret Eugenics Conference Uncovered at University College London
  2. Like Humans, Walruses and Bats Cuddle Infants on Their Left Sides
  3. How Do Infant Immune Systems Learn to Tolerate Gut Bacteria?
  4. Scientists Continue to Use Outdated Methods
AAAS