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drug development
Apr 1, 2024
| 3 min read
MEGA CRISPR: Engineering Better Immunotherapies with RNA Editing
Multi-targeted Cas13 screens help researchers avoid permanent DNA cuts and evade T cell exhaustion.
Apr 1, 2024
| 2 min read
Enter Our 2024 Top 10 Innovations Contest
Explainable AI for Rational Antibiotic Discovery
Advancing Clinical Research Through Effective Data Delivery
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drug development
Starting Up a New Endeavor
Shelby Bradford, PhD
| Apr 1, 2024
| 2 min read
In his lab, Hashim Al-Hashimi investigated how RNA molecules move. Along the way, he founded a company.
Single Domain Antibodies: Small but Mighty Therapeutics
The Scientist
| Mar 22, 2024
| 1 min read
Discover the benefits of VHH antibody-based therapies.
Building Advanced Cell Models for Toxicity Testing
The Scientist
Staff
| 1 min read
In this webinar, Kevin Grady and Manisha Nautiyal will outline how to make predictive 2D and 3D models for pharmacological toxicity testing.
Infographic: Vaccinating Against Tumors
Shelby Bradford, PhD
| Mar 15, 2024
| 1 min read
Cancer vaccines offer the opportunity to use the patient’s own immune system in the fight against tumors.
Delivering Prime Editors With Virus-like Particles
Deanna MacNeil, PhD
| Mar 11, 2024
| 3 min read
An iterative engineering approach to improve prime editor delivery helped scientists correct genetic vision defects in mice.
How Cloud Labs and Remote Research Shape Science
Priyom Bose, PhD
| 6 min read
Remote research via cloud labs makes it possible for scientists to conduct complex experiments from a distance.
Making Moves Toward Cell Therapy for Diabetes
Deanna MacNeil, PhD
| Feb 20, 2024
| 3 min read
A step-by-step cell culture process may improve the quantity and quality of cell replacement therapies.
Turmeric Tackles Antimicrobial Resistance
Danielle Gerhard, PhD
| Jan 1, 2024
| 2 min read
An active ingredient in turmeric interacts with light to resensitize pathogens to antibiotics.
High Throughput Screening Models Ramp up Lead Discovery
The Scientist
| 1 min read
Fast, automated, and relevant biological tools and technologies help researchers hunt for more hits.
Curiosity and Compassion Fuel Rare Disease Research
The Scientist
Staff
| Jan 1, 2024
| 1 min read
Lauren Drouin shares how personal connections and scientific curiosities drive her work on gene therapy viral vectors.
Infographic: Phage Display Allows Rapid Screening of Millions of Peptides
Shelby Bradford, PhD
| Dec 4, 2023
| 3 min read
A viral protein expression method links proteins and their coding instructions, enabling easier target identification for downstream analysis.
From the Expert: Click Chemistry and Bioorthogonal Applications
The Scientist
| 1 min read
Carolyn Bertozzi discusses her recent work on targeted degradation therapies that rely on bioorthogonal chemistry.
Phage Display: Finding the One in a Million
Shelby Bradford, PhD
| Dec 4, 2023
| 10+ min read
A combinatorial approach enabled high-throughput screening of protein libraries for desired target binding.
Engineered RNA Export From Living Cells
Danielle Gerhard, PhD
| Dec 1, 2023
| 1 min read
A nondestructive approach for packaging, exporting, and delivering RNA provides a glimpse into the dynamic lives of cells.
Making Connections: Click Chemistry and Bioorthogonal Chemistry
Deanna MacNeil, PhD
| 5 min read
Simple, quick, and modular reactions allow researchers to create useful molecular structures from a wide range of substrates.
Mean, Green, Antibody-producing Machines
Shelby Bradford, PhD
| Dec 1, 2023
| 2 min read
A plant-based monoclonal antibody goes head-to-head with its commercial counterpart to target tumors in mice.
Organoids: The New Frontier
The Scientist
| Nov 22, 2023
| 1 min read
Explore the latest in organoid production for studying development, disease, and drug screening.
Host Cell Protein and Impurity Risk Mitigation in Monoclonal Antibody Therapeutic Manufacturing
The Scientist
Staff
| 1 min read
In this webinar, Andrew Hamilton and Joe Hirano will explore how to detect and remove host cell proteins and other impurities during biologics manufacturing.
A Double Lock Gates Calcium Signaling
Danielle Gerhard, PhD
| Nov 13, 2023
| 6 min read
Recent studies settle a debate over how the second messenger NAADP, with no known binding site, evokes calcium release from ion channels.
A New Drug Fixes a Leak Caused by Bacteria
Kamal Nahas, PhD
| Nov 8, 2023
| 5 min read
Researchers discovered how virulent bacterial proteins leech nutrients from plant cells, leading to a potential treatment for diseased crops.
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