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Multidrug combinations lead to better results for cancer patients, but efficiently identifying them is proving difficult.

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image: How to Successfully Collaborate with Industry

How to Successfully Collaborate with Industry

By Ashley P. Taylor | March 1, 2018

In efforts to translate basic-science results into pharmaceuticals and other technologies, success cannot be taken for granted.

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One dose of the medication, called Xofluza, cripples influenza by interfering with an enzyme critical for viral replication.  

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Pharmaceutical giant Sanofi to take over hemophilia drugmaker Biovertiv, while Celgene will buy cancer drugmaker Juno Therapeutics.

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image: Opinion: Label Drugs That Are Tested on Animals

Opinion: Label Drugs That Are Tested on Animals

By Shaun Khoo | January 16, 2018

Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.

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image: Child Receives Transgenic Skin

Child Receives Transgenic Skin

By Ruth Williams | January 1, 2018

A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and resolved a dermatology debate to boot.

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image: Infographic: A Painful Pathway

Infographic: A Painful Pathway

By Catherine Offord | January 1, 2018

Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.

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image: Painful Realities

Painful Realities

By The Scientist Staff | January 1, 2018

Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.

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image: Sex Differences in Opioid Analgesia: A Complicated Picture

Sex Differences in Opioid Analgesia: A Complicated Picture

By Catherine Offord | January 1, 2018

Researchers are beginning to tease apart the mechanisms underlying differences in how males and females respond to powerful painkillers.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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