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image: Novel Analgesics at a Snail’s Pace

Novel Analgesics at a Snail’s Pace

By Bob Grant | January 1, 2018

Studying cone snail venom has yielded novel pain pathways, but the peptides that function as toxins are difficult to translate into drugs.

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image: Researchers Mine Centipede Toxins for Analgesics

Researchers Mine Centipede Toxins for Analgesics

By Catherine Offord | January 1, 2018

Venomous centipedes may harbor a clue to the creation of a successful pain-killing compound for humans.

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image: Sea Anemone Toxin Could Treat Autoimmunity

Sea Anemone Toxin Could Treat Autoimmunity

By Jef Akst | January 1, 2018

If successful, the treatments could alleviate patients’ pain by reducing inflammation.

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image: Sourcing Painkillers from Scorpions’ Stings

Sourcing Painkillers from Scorpions’ Stings

By Abby Olena | January 1, 2018

Compounds in the arachnids’ venom interact with ion channels to both cause and block pain.

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image: Toxin from a Dangerous Fish Delicacy

Toxin from a Dangerous Fish Delicacy

By Kerry Grens | January 1, 2018

In tiny doses, the pufferfish’s tetrodotoxin can be turned into a pain-relieving ion channel blocker.

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image: Snake Venoms Cause and Block Pain

Snake Venoms Cause and Block Pain

By Kerry Grens | January 1, 2018

Painful snake bites may hold clues to developing analgesic drugs.

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image: Hormonal Male Contraceptive to Enter Clinical Trial

Hormonal Male Contraceptive to Enter Clinical Trial

By Jef Akst | December 21, 2017

The gel, which men rub on their upper bodies daily, delivers synthetic progestin to block the testes from producing normal levels of sperm.

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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By Katarina Zimmer | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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If approved, patisiran will be the first RNAi therapeutic on the market. 

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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By Amanda B. Keener | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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