drug development

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

This lifelike replica of the one-centimeter, 500-million-year-old arthropod Agnostus pisiformis was reconstructed from the animal’s ancient fossils.

Scientific misconduct motivated Yoshihiro Sato’s three additional retractions last month; his institution doesn’t respond. 

Some researchers have already been negatively affected by the U.K.’s decision to leave the European Union, though opinions on the eventual outcome remain mixed.

By stifling autophagy in the motor neurons of a mouse model of amyotrophic lateral sclerosis (ALS), scientists stem later-stage disease progression.

An aide to President Donald Trump has final say over grants at the Environmental Protection Agency and has nixed close to $2 million of the agency’s awards.

This 10-centimeter-wide pig eye replica includes even the most intricate of blood vessels, some no wider than 30 micrometers.

In the developing Drosophila visual system, signals from glia cultivate the growth of neurons from immature cells.

Using new nanochip technology, scientists can measure the light emitted by engineered fluorescing bacteria.

To tease apart brain regions involved in forming versus remembering memories, scientists engineered mice whose brain cells could be manipulated and tagged.

Sparked by a tweet from a Philadelphia scientist, the March for Science–Houston has launched a database of facilities offering to host reagents and researchers. 

Techniques for comparing the relative abundances of glycans and glycoproteins in clinical samples

In a developing chicken embryo, skin cells pull on each other, forming multicellular mounds that eventually turn into properly-spaced feathers.

Experiments that place untethered fish, flies, and mice in simulated environments give clues about the animals’ social behavior.

In a memo to federal agencies, the administration highlights defense and security, leaves off Earth and climate science, and limits the scope of basic research.

The mini machines treated infection somewhat better than antibiotics plus the typical proton pump inhibitor medication. 

A fraught market for the barbiturates prescribed to terminally ill patients who choose to end their lives has physicians turning to options outside big pharma.

Rush Holt of AAAS talks with The Scientist about the upcoming gathering and collaborations—past, present, and future—between the two countries.

Scientists tout this lens-free holographic technique as a cost-effective alternative to standard tissue biopsies. 

Using human pluripotent stem cells, scientists engineered an amniotic sac-like structure, potentially useful for uncovering the elusive cellular signals that lead to infertility.