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image: Toxin from a Dangerous Fish Delicacy

Toxin from a Dangerous Fish Delicacy

By Kerry Grens | January 1, 2018

In tiny doses, the pufferfish’s tetrodotoxin can be turned into a pain-relieving ion channel blocker.

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image: Snake Venoms Cause and Block Pain

Snake Venoms Cause and Block Pain

By Kerry Grens | January 1, 2018

Painful snake bites may hold clues to developing analgesic drugs.

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image: Hormonal Male Contraceptive to Enter Clinical Trial

Hormonal Male Contraceptive to Enter Clinical Trial

By Jef Akst | December 21, 2017

The gel, which men rub on their upper bodies daily, delivers synthetic progestin to block the testes from producing normal levels of sperm.

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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By Katarina Zimmer | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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If approved, patisiran will be the first RNAi therapeutic on the market. 

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image: Infographic: Breaking into the Brain

Infographic: Breaking into the Brain

By Amanda B. Keener | November 1, 2017

The blood-brain barrier is a collection of specialized cells and proteins that control the movement of molecules from the blood to the central nervous system.

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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image: Tiny Motors Deliver Ulcer Medication in Mouse Stomachs

Tiny Motors Deliver Ulcer Medication in Mouse Stomachs

By Shawna Williams | August 17, 2017

The mini machines treated infection somewhat better than antibiotics plus the typical proton pump inhibitor medication. 

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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By Kerry Grens | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By Kerry Grens | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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