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image: Eat Yourself to Live: Autophagy’s Role in Health and Disease

Eat Yourself to Live: Autophagy’s Role in Health and Disease

By Vikramjit Lahiri and Daniel J. Klionsky | March 1, 2018

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

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The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  

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The company’s recent effort to find new treatments for Alzheimer’s ended in disappointment.

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image: Optogenetic Therapies Move Closer to Clinical Use

Optogenetic Therapies Move Closer to Clinical Use

By Shawna Williams | November 16, 2017

With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.

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image: Research Links Gut Health to Neurodegeneration

Research Links Gut Health to Neurodegeneration

By Jef Akst | November 13, 2017

Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.

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image: A Potential Remedy for the Aging Brain

A Potential Remedy for the Aging Brain

By Aggie Mika | August 8, 2017

In mice, injected fragments of a naturally occurring protein boost memory in young and old animals and improve cognition and mobility in a model of neurodegenerative disease. 

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image: Deep Brain Stimulation Without Surgery

Deep Brain Stimulation Without Surgery

By Aggie Mika | June 1, 2017

Using interfering high-frequency currents applied to the surface of the mouse skull, scientists can noninvasively target brain regions buried below the cortical surface. 

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image: Exploring the Mechanisms of Music Therapy

Exploring the Mechanisms of Music Therapy

By Elizabeth Stegemöller | March 1, 2017

The principles of neuroplasticity may underlie the positive effects of music therapy in treating a diversity of diseases.

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image: As the Brain Ages, Glial-Cell Gene Expression Changes Most

As the Brain Ages, Glial-Cell Gene Expression Changes Most

By Ashley P. Taylor | January 10, 2017

Researchers describe how gene expression in different human brain regions is altered with age.

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